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Well, it's like comparing Unreal Engine 3 and Cry Engine 2. They both have different approaches and trade-offs.

Unreal Engine 3
-Runs on a wider range of hardware, runs faster on older hardware.
-Able to spend more processing power on fancy effects.

Cry Engine 2
-Runs on fewer cards, requires faster hardware.
-Spends most of its processing power on lighting.

The main point is in Cry Engine 2 they made the decision to use an expensive lighting system with all real-time shadows. This might or might not be desirable, depending on your game type and target specs. For a spooky horror game or an MMPORG with a day-night cycle, the real-time lighting is ideal. For a racing game, lighting might not make as big a difference, so you might want to target a wider range of users and skip the dynamic lighting.

So it really depends on what tradeoff you want. DBPro will probably be faster, especially on older hardware, and will run on a wider range of cards. If I used DBPro I would focus on lots of fancy graphical effects since you will save a lot of GPU power by not rendering dynamic soft shadows. If you want real-time lighting, Leadwerks provides that. It looks great, but is a computationally expensive process.

Fortunately, The Game Creators provides both approaches so you can choose what is best for your game type and target market.

Most of us agree that you should use the right tool for the job at hand. If you need C++ and a game library; you use them. If it is not necessary, then use the best tool to get the job done. Weather that is DBP, C or Java. DBP's strengths have been covered as many times as it's points of weakness.