I just bought a small one about a month ago, and I love it.
When writing or drawing with it, it feels more like writing on paper with a pencil(and even sounds like it a bit.) I could see how a medium or even a large one would be handier, but I bought a small bamboo pad and have gotten used to it and I like it lots. Also, resting your hand on the pad will not affect drawing. The pad is only affected by the stylus. The one thing that took a little getting used to, (which is actually quite awesome) is that the pad represents the screen when writing. The top left corner of the pad is the top left corner of the screen, the bottom right is the bottom right of the screen, and the middle is the middle. In essence, you could draw something on paper, place it on the pad, then trace it while picking the pen off the paper as much as you want starting on different spots on the paper and still get a duplicate on screen.
I would suggest getting one. If you've got the money, I would also suggest getting a bigger one. That way, when you fall in love with it, you won't have to justify owning two just to get a bigger one.
There's something in this room that makes you can't speak well.