My friend went through a cycle or two of creatine and it definitely helped build his muscle mass and he felt good. He drank a ton of water anyway and still does, so I don't think it affected him that much.
@Seppuku, I wouldn't give up on supplements, I'm doing HCG right now (yes, the pregnant women hormone--the stuff I used is synthesized though), and it's awesome. It has the potential to be abused like a stupid lose-weight-quick gimmick, but if you follow the proper routine you get good results. I'm on day 24 of a 30-day cycle, and I've lost 32 pounds.
HCG itself doesn't help you lose weight, it merely encourages weight loss in the right places (gut, chest, neck fat, etc.) without leaving you looking gaunt. It also prevents your body from going into "survival mode" where it will try to store as much as it can in fat.
When on HCG you can't eat any carbohydrates, starch, sugary foods (light sugar is okay like in fruits and veggies like onions), or fatty oils. You eat 500 calories a day (300 meat, 120 fruit, 80 vegetable). You're not supposed to exercise because of the low caloric intake, rather just let your body naturally start burning fat for the energy it needs, with HCG helping to point it in the right direction. I take a small dosage of an appetite suppressant to help keep up energy and prevent hunger pains. Not everyone needs it though.
After 30 days of taking the injections or oral supplements (injections FTW, they're more manly

), you begin a 3-week maintenance period in which you gradually increase the amount of calories you eat daily. You're still limited as to what you can eat, but after the first few days you can have a small amount of dairy, then a couple weeks later some starches, then sugar, and finally after the 3-weeks you can have carbohydrates.
The goal is to have this diet change your appetite and your body's metabolism. Once you begin the 3-week maintenance, you can start some light workouts, and by the end of it if you maintain a good diet and workout routine, any amount of weight you regain will be minimal. My parents have done it, and even after screwing up on their diet a couple of times (like visiting me in NY and having some brick oven pizza), they only regained 8 or so pounds out of the 30ish pounds they lost.
My meals usually consist of a grilled chicken breast, a serving of vegetables like spinach, asparagus, or grilled onions, and a serving of apples or strawberries. You can even have a wee bit of steak.
Aside from a desire for pizza, I'm feeling and looking great. My asthma's improved, and (partially thanks to the appetite suppressant) I haven't had any problems with my energy levels throughout the day. I do pee a lot, but that's because you're burning a lot of fat throughout the day, and the waste has to go
somewhere. I never drank that much water, so I increased how much I drank daily when I started, and I think that helped increase my pounds per day ratio.