Why are you looking at pcb this early? buy some breadboard and bell wire, look at arm devboards, the embedded/uC ones are ~£35 that I linked you to in another thread.
pcb design comes at the end, when you know exactly what you are doing, prototype boards should be done by hand, you shouldn't need that many components really. Consider using a standard controller port like the megadrive/genisis ones, I think it's the same as a serial port, and the wiring is really simple, it means you don't need to make controllers to test the rest of the system.
AMD AthlonX2 5000 black edition @2.8ghz, 4gb pc5400, AMD/ATi hd3850, creative xfi music, 24" hp widescreen 1920x1200 + 22" zalman trimon 3D 1680x1050, ECS KA3 MVP mobo