I used to manage a network with numerous Dellgx280's ~ not they any more problematic than every other brand I've dealt with (honestly had more issue with IBM Thinkpads,, and enough headaches with Compaqs (pre HP take over) than I care to recall) ~ But I would suggest routinely using compressed air for the power-supply's fan and associate case airflow ports, as they seemed to be my biggest problem with this model.
Perhaps it was due to a dusty environment, but this model (as well as the gx260) were particularly sensitive to heating/breathing problems. The power supply is proprietary to DELL (though there may be generics avail, it's not your everyday PS that people have kicking around). I had far too many fail/burn-out on me.
I wasn't a fan of there quick release rail system (it made it quick to move things around),, but in my environment it actually meant more work for me to replace hardware,, having to attach their rails and such. I personally wasn't a fan of the clam-shell case,, but I got used to it. Shouldn't be as big of an issue dealing with one of them.
~ZENassem