I have DBPro running on Windows 10 without problems. My copy is installed in my Documents folder and I think I have the latest Synergy Editor - there used to be a link to it among the sticky threads on this board. I'm also using Upgrade U77RC7 which you can find here somewhere.
One other thing to check is your project folder. Sometimes some temporary files get left behind when you compile and they prevent further compilation in that project folder. Haven't seen that error for a while though.
Which version are you using? If you're using an old version you might need to download an update.