If you like Heroes you will love Runaways, it's a comic about a group of children who find out that their parents are super-villains.
It's set in the normal Marvel universe, but it's on the east coast (Miami I think), so it's kind of a running joke that the proper super heroes like Spider-man and Daredevil are always in New York, they do exist though and they are kind of like celebrities.
You can get the mini-sized compilations pretty cheaply.
100 Bullets is just simply amazing I don't want to ruin it at all because it is so tightly plotted, everything interweaves and stuff... basically it's a crime noir story about a mysterious agent who offers random* people a briefcase with a gun and 100 bullets that can't be traced, and irrefutable evidence that there is someone out there that has wronged them. Like, if someone's brother has been killed, he'll give them a briefcase with a picture of who did it in and the gun. Basically he gives people the chance to get away with murder (not everyone takes the gun, or suceeds in getting revenge).
*
Powers is a kind of mixture of the two, it's set in a universe where super powers aren't secret and are relatively common (but not trivial), it's about two homicide detectives who are in the Powers Division, ie. they investigate murders involving powers. Best written comic there is at the moment.
-= Out here in the fields, I fight for my meals =-
